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4 Application prospects of modulating gut microbiota in the treatment of PCOS Given the significant role of gut microbiota dysbiosis in the pathogenesis of PCOS, targeted modulation of the gut microecology in affected patients holds promise as a novel treatment strategy

Dulaglutide and Liraglutide : While effective, these medications may result in slightly less weight loss compared to Semaglutide and Tirzepatide, with average reductions around 5-10%

65% of 125,474 real-world GLP-1 users had discontinued within 12 months

In trial comparisons, retatrutide displayed more promising results regarding weight loss percentages